Project Three:

Nanoparticles for photodynamic therapy

Nancy L. Oleinick, Ph.D. Department of Radiation Oncology
Clemens Burda, Ph.D. Department of Chemistry
Malcolm E. Kenney, Ph.D. Department of Chemistry
Case Western Reserve University


Notice: These publications (studies or reports) were prepared under a grant from the State of Ohio, Department of Development. The content reflects the views of Case Western Reserve University and does not nesessarily reflect the veiws of the State of Ohio, Department of Development or the Third Frontieer Commission.


I.J. Macdonald and T.J. Dougherty
"Basic principles of photodynamic therapy"
J. Porphyrins Phthalocyanines, 105-129, 2001

T.J. Dougherty
"An update on photodynamic therapy applications"
J Clin Laser Med Surg, 20, 3-7, 2002

N.L. Oleinick, A.R. Antunez, M.E. Clay, B.D. Rihter, and M.E. Kenney
"New phthalocyanine photosensitizers for photodynamic therapy"
Photochem. Photobiol., 57, 242-247, 1993

N.L. Oleinick, R.L. Morris, and I. Belichenko
"The role of apoptosis in response to photodynamic therapy: what, where, why, and how"
Photochem Photobiol Sci, 1, 1-21, 2002

I. Roy, T.Y. Ohulchanskyy, H.E. Pudavar, E.J. Bergey, A.R. Oseroff, J. Morgan, T.J. Dougherty, and P.N. Prasad
"Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: a novel drug-carrier system for photodynamic therapy"
J Am Chem Soc, 125, 7860-5, 2003

L.-Y. Xue, S.-M. Chiu, A. Fiebig, D.W. Andrews, and N.L. Oleinick
"Photodamage to multiple bcl-xL isoforms by photodynamic therapy with the phthalocyanine photosensitizer Pc 4"
Oncogene, 22, 9197-204, 2003

L.-Y. Xue, S.-M. Chiu, and N.L. Oleinick
"Photochemical destruction of the Bcl-2 oncoprotein during photodynamic therapy with the phthalocyanine photosensitizer Pc 4"
Oncogene, 20, 3420-7, 2001

R.L. Morris, K. Azizuddin, M. Lam, J. Berlin, A.L. Nieminen, M.E. Kenney, A.C. Samia, C. Burda, and N.L. Oleinick
"Fluorescence resonance energy transfer reveals a binding site of a photosensitizer for photodynamic therapy"
Cancer Res, 63, 5194-7, 2003

A.C. Samia, X. Chen, and C. Burda
"Semiconductor quantum dots for photodynamic therapy"
J Am Chem Soc, 125, 15736-7, 2003